Safety of Endoscopic Thyroidectomy Via Retro-Auricular Single-Site Approach, Transoral Approach and Transareola

Sun Yat-sen University

Status: Completed

Conditions: Papillary Thyroid Carcinoma

Treatments: Procedure: Retro-Auricular Single-Site Endoscopic Thyroidectomy; Procedure: Transareola Endoscopic Thyroidectomy; Procedure: Transoral Endoscopic Thyroidectomy Vestibular Approach

Study type: Interventional

Funder types: Other

Identifiers

NCT05760690

B2022-359-01

Details and patient eligibility

About

The goal of this retrospective study is to compare the safety and efficiacy of endoscopic thyroidectomy via retro-auricular single-site approach, transoral endoscopic thyroidectomy vestibular approach and transareola approach.

Enrollment: 160 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age 18-70 years old, no gender restrictions.
2. Fine-needle aspiration cytology(FNA) confirmed papillary thyroid carcinoma(PTC).
3. Early stage PTC (stage T1N0M0).
4. Preoperative ultrasonography showed unilateral glandular lobe malignant tumor and the largest diameter was not more than 2cm, without cervical lymph node metastasis and extensive metastasis.
5. Patients undergoing thyroid lobectomy and central lymph node dissection.
6. Patients who have signed an approved Informed Consent.

Exclusion criteria

1. Patients who do not accept case data collection for various reasons.
2. The clinical data unfit this study (at the discretion of the investigator).
3. Patients who have undergone neck surgery or radiotherapy before this trail.
4. Patients who have uncontrolled hyperthyroidism.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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160 participants in 3 patient groups

Retro-Auricular Single-Site Endoscopic Thyroidectomy group

Experimental group

Description:

Patients in the retro-auricular single-site endoscopic thyroidectomy (RASSET) group will receive endoscopic thyroid lobectomy and central lymph node dissection.

Treatment:

Procedure: Retro-Auricular Single-Site Endoscopic Thyroidectomy

Transoral Endoscopic Thyroidectomy Vestibular Approach group

Active Comparator group

Description:

Patients in the Transoral Endoscopic Thyroidectomy Vestibular Approach group will receive endoscopic thyroid lobectomy and central lymph node dissection.

Treatment:

Procedure: Transoral Endoscopic Thyroidectomy Vestibular Approach

Transareola Endoscopic Thyroidectomy group

Active Comparator group

Description:

Patients in the Transareola Endoscopic Thyroidectomy group will receive endoscopic thyroid lobectomy and central lymph node dissection.

Treatment:

Procedure: Transareola Endoscopic Thyroidectomy