Safety of Intravenous Lidocaine Infusions

Lawson Health Research Institute

Status: Completed

Conditions: Neuropathic Pain

Study type: Observational

Funder types: Other

Identifiers

NCT01091935

R-08-341

15240E (Other Identifier)

Details and patient eligibility

About

The purpose of this study is to prospectively determine the side effects profile in adults with neuropathic pain receiving intravenous infusions of lidocaine 5 mg per kg of lean body weight, infused over 45 minutes.

Full description

Eligibility Criteria:

Adults > 18 yrs with chronic central or peripheral neuropathic pain at the St Joseph's Health Care Pain Clinic between June and December 2009.

Outcome measures: All side effects spontaneously reported. Sedation, nausea, dizziness by Visual Analog Score Q 15 minutes; hemodynamic data q 5 minutes during and after infusion for 30 minutes.

Daily diary of side effects and Visual Analogue score of Pain for 7 days post-infusion.

Enrollment: 70 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult outpatients > 18 years < 80 years diagnosed with chronic neuropathic pain

Exclusion criteria

• Unable to provide informed consent
• Unable to speak and understand English
• Liver, kidney, or cardiac failure
• Allergy to Lidocaine

Trial design

70 participants in 1 patient group

Lidocaine

Description:

Adults \>18 yrs , attending St Joseph's Health Care Pain Clinic with a diagnosis of chronic neuropathic pain who are being treated with an lidocaine infusion of 5 mg/kg over 45 minutes Consecutive patients from two time periods: 1. June 15 to August 21, 2009 2. October 15-Dec 22,2009