Safety of Remifentanil Infusion

Diskapi Teaching and Research Hospital

Status and phase: Completed; Phase 4

Conditions: Urinary Tract Problem

Treatments: Drug: remifentanil

Study type: Interventional

Funder types: Other

Identifiers

NCT01303627

DiskapiTRH

Details and patient eligibility

About

The effect of maintenance remifentanil infusion with target controlled infusion during laryngeal mask airway removal on hemodynamic parameters and emergence quality is going to be investigated.

Full description

In all patients (control group and remifentanil group induction of anesthesia will be achieved with desflurane and remifentanil.Anesthesia will be maintained with remifentanil (1-4 ng/mL) by TCI target controlled infusion, and desflurane . Throughout the surgery hemodynamic parameters are going to be recorded. As soon as the surgery has been finished, in control group remifentanil infusion and desflurane inhalation is going to be stopped.In remifentanil group,desflurane inhalation is going to be stopped and remifentanil infusion will be maintained until the removal of LMA. During the emergence period the time of eye opening, hemodynamic parameters and emergence quality (score 1-2)are going to be recorded.

Enrollment: 42 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA I-II status
• aged 18-60 years old
• presenting for ureterorenoscopy

Exclusion criteria

• history of hypertension
• asthma and chronic obstructive lung disease
• recent respiratory tract infections

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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42 participants in 2 patient groups

ultiva,remifentanil,opioid,analgesic

Active Comparator group

Description:

Remifentanil:1.5ng/ml remifentanil infusion maintained at the end of the surgery

Treatment:

Drug: remifentanil

control

No Intervention group

Description:

Control:Remifentanil stopped at the end of the surgery