Safety of Umbilical Cord Mesenchymal Stem Cell Local Intramuscular Injection for Treatment of Uterine Scars

Maternal and Child Health Hospital of Foshan

Status and phase: Withdrawn; Phase 1

Conditions: Uterine Scar

Treatments: Other: Umbilical cord MSCs

Study type: Interventional

Funder types: Other

Identifiers

NCT03181087

MCHHFoshan-1701

Details and patient eligibility

About

The purpose of this study is to evaluate the safety of umbilical cord mesenchymal stem cell local intramuscular injection for treatment of uterine scars by a prospective, single-center, open, and single-arm clinical trial.

Sex: Female

Ages: 21 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Primiparous women receiving cesarean delivery
• Ages between 21-35 years
• Gestation ages ≥ 37 weeks and < 42 weeks
• Willing to comply with study dosing and completed the entire course of the study
• Willing to give and sign an informed consent form and a photographic release form

Exclusion criteria

• Fibroids
• Placenta previa
• Placenta abruption
• Multiple gestation
• Antepartum hemorrhage
• Preeclampsia/Eclampsia
• Hepatic or renal dysfunction
• Any systemic uncontrolled disease
• Inability to provide consent

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 1 patient group

Umbilical cord MSCs Group

Experimental group

Description:

1\*10\^7 Umbilical cord Mesenchymal Stem Cells (MSCs)

Treatment:

Other: Umbilical cord MSCs