Saliva Levels of S100A12, CRP, Fetuin-A in Periodontal Disease Patients

T.C. ORDU ÜNİVERSİTESİ

Status

Completed

Conditions

Periodontal Inflammation

Treatments

Diagnostic Test: salivary samples

Study type

Observational

Funder types

Other

Identifiers

NCT03345745

OrduUniversityDentistry

Details and patient eligibility

About

Hs-CRP, Fetuin-A and S100A12 are acute phase proteins associated with many systemic diseases and conditions. The aim of this study was to determine the clinical parameters and salivary Hs-CRP, Fetuin-A and S100A12 levels before and after non-surgical periodontal treatments in the patients with periodontal diseases.

A total of 54 subjects were divided in to three groups; periodontally healthy (n: 18), gingivitis (n: 18), chronic periodontitis (n: 18). Clinical periodontal parameters, salivary Hs-CRP, Fetuin-A and S100A12 levels and salivary flow rates were evaluated at baseline and a month after the treatments. Salivary Hs-CRP, Fetuin-A and S100A12 levels were assayed by ELISA.

Enrollment

54 patients

Sex

All

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

never-smokers no history of systemic disease no patients had been under periodontal therapy and medicine for at least 6 months before the study no pregnancy or lactation no alcohol or antioxidant vitamin consumption.

Exclusion criteria