Salivary Catecholamines in Aphthous Stomatitis (Canker Sores)

University of California (UC) Davis

Status: Withdrawn

Conditions: Canker Sore

Study type: Observational

Funder types: Other

Identifiers

NCT00556686

200614581

Details and patient eligibility

About

The purpose of this study is to examine how compounds produced in patients with canker sores affect wound healing.

Full description

The purpose of this study is to determine if salivary catecholamines are elevated in patients with the disease aphthous stomatitis. The results of this study will be combined with those performed in collaboration with a co-Investigator to understand the effects of catecholamines on mucosal wound healing and oral epithelial cell migration.

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 18 or older, both genders
• History of recurrent aphthous ulcers with 4 or more episodes per year

Exclusion criteria

• History of salivary gland disease including Sjogren's disease, parotitis, and sialolithiasis
• History of benign or malignant salivary gland tumor
• History of celiac disease, ulcerative colitis or Crohn's disease
• Patients on medications that affect salivary flow such as anti-depressants and anti-cholinergic medications

Trial design

0 participants in 2 patient groups

1

Description:

Individuals with a history of canker sores.

2

Description:

Individuals with no history of canker sores.