Salivary Interleukin-32, Interleukin-10, Interleukin-6 and Tumor Necrosis Factor-alpha Levels in Children

Aydin Adnan Menderes University

Status: Completed

Conditions: Early Childhood Caries

Treatments: Diagnostic Test: ELISA

Study type: Observational

Funder types: Other

Identifiers

NCT04958005

2020/190

Details and patient eligibility

About

This study aimed to evaluate the levels of interleukin 10, interleukin 6, interleukin 32 and tumor necrosis factor-alpha (TNF-α) in saliva of children with early childhood caries.

Full description

Fifty six children ( 28 with early childhood caries and 28 without early childhood caries ; age range 3-6 years) will be recruited for the study. Probing pocket depth (PPD), gingival index (GI) and plaque index (PI) will be recorded and saliva samples will be collected. Interleukin-32, Interleukin-10, Interleukin-6 and TNF-α will be analyzed in saliva samples by ELISA.

Enrollment: 58 patients

Sex: All

Ages: 3 years to 70 months old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children with untreated early chilhood caries
• Age between 3 and 6 years

Exclusion criteria

• Having a systemic problem or mental retardation
• Children with treated caries

Trial design

58 participants in 2 patient groups

Children with early chilhood caries

Description:

Early chilhood caries group

Treatment:

Diagnostic Test: ELISA

Without early chilhood caries

Description:

Control group

Treatment:

Diagnostic Test: ELISA