Salmeterol Effect on Exercise Performance

University of Copenhagen

Status: Enrolling

Conditions: Healthy

Treatments: Drug: Salmeterol; Drug: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT06655012

SALM_acute

Details and patient eligibility

About

The purpose of the project is to investigate the muscle anabolic response to acute beta2-adrenergic stimulation in young healthy men and women.

Enrollment: 36 estimated patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Inclusion Criteria:
• Age 18-40
• Physically active >5 hours a week
• Maximum oxygen uptake classified as high or very high

Exclusion criteria

• Active smoker currently or within the past 5 years
• Regular intake of medication deemed by the responsible study physician to affect the test parameters (hormonal contraception is accepted for women)
• Chronic or acute illness deemed by the responsible study physician to affect the test parameters
• Deviation from the study protocol
• Lean mass index >21 kg/m²
• Pregnancy
• Smoker
• Blood donation during the past 3 months

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Quadruple Blind

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36 participants in 2 patient groups, including a placebo group

Salmeterol

Experimental group

Description:

Participants are administered salmeterol from an inhaler device

Treatment:

Drug: Salmeterol

Placebo

Placebo Comparator group

Description:

Participants are administered placebo from an inhaler device

Treatment:

Drug: Placebo