Sarcopenia and Intervention Physical Therapy

Pharos University in Alexandria

Status: Not yet enrolling

Conditions: Sarcopenia

Treatments: Device: Neuromuscular Electrical Stimulation (NMES) Group,Resistance + BFR Group

Study type: Interventional

Funder types: Other

Identifiers

NCT07013604

sarcopenia

Details and patient eligibility

About

To evaluate and compare the effectiveness of neuromuscular electrical stimulation (NMES) and low-load resistance training with blood flow restriction (BFR) in improving muscle mass, strength, functional performance, and quality of life in elderly individuals diagnosed with sarcopenia

Full description

Sarcopenia, the age-related decline in muscle mass, strength, and function, significantly affects the health and independence of elderly individuals. It increases the risk of frailty, falls, and disability. Neuromuscular electrical stimulation (NMES) and low-load resistance training with blood flow restriction (BFR) are promising rehabilitation strategies for older adults with limited physical capacity. This study aims to compare the effectiveness of NMES and BFR in managing sarcopenia and improving physical and functional outcomes in the elderly

Enrollment: 60 estimated patients

Sex: All

Ages: 60 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Older age (≥ 60-75 years)

Low muscle strength (e.g., low handgrip strength)

Low muscle mass (e.g., ASM/height² below cutoff)

Exclusion criteria

• heart disese
• kidny disese
• autoimune disese
• cognetive disorder
• sever form of sarcopenia

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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60 participants in 3 patient groups, including a placebo group

Neuromuscular Electrical Stimulation (NMES) Group

Experimental group

Description:

Participants receive neuromuscular electrical stimulation (NMES) targeting the quadriceps and hamstrings, 30 minutes per session, 3 times per week for 8 weeks

Treatment:

Device: Neuromuscular Electrical Stimulation (NMES) Group,Resistance + BFR Group

Resistance + BFR Group

Experimental group

Description:

Participants perform low-load resistance training (30% 1RM) combined with blood flow restriction using pneumatic cuffs, 30 minutes per session, 3 times per week for 8 weeks

Treatment:

Device: Neuromuscular Electrical Stimulation (NMES) Group,Resistance + BFR Group

Control Group

Placebo Comparator group

Description:

Participants receive placebo treatment by being connected to a neuromusculoskeletal device that is turned off (no actual stimulation), with no active intervention during the 8-week period

Treatment:

Device: Neuromuscular Electrical Stimulation (NMES) Group,Resistance + BFR Group