Sarcopenia and Risk of Falls in Patients With Major Chronic Diseases

Changhua Christian Medical Foundation

Status: Completed

Conditions: Osteoporosis; Chronic Kidney Diseases; Stroke; Cancer

Treatments: Behavioral: elastic band strengthening exercise; Dietary Supplement: diet counseling

Study type: Interventional

Funder types: Other

Identifiers

NCT03798418

CCH-170208

Details and patient eligibility

About

The objective of this study is to investigate the effects of therapeutic exercise and nutrition intervention for sarcopenia and risk of falls in patients with major chronic diseases. The outcomes will be analyzed regarding muscle strength, quality, and volume, etc., balance and gait, bone density, body composition, fall and quality of life after the intervention.

Full description

The main common chronic diseases in the elderly such as stroke, osteoporosis, chronic kidney disease and cancer, have been regarded as the fall high-risk patients. These patients are considered to be at risk for sarcopenia due to decreased exercise, nutritional status, and other reasons. Sarcopenia can be diagnosed and intervened effectively to delay the vicious cycle of health. Past studies have pointed out that in addition to drug intervention, treatment for sarcopenia must be accompanied by appropriate exercise and nutritional intervention (such as protein supplements, vitamin D) in order to achieve the best prevention and treatment.

Enrollment: 186 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

• Inclusion Criteria:

  1. 55-85 years old
  2. 3-6 months after onset
  3. walk independently for at least 10m

• Exclusion Criteria:

  1. lower limb Brunnstrom stage >5
  2. combine other neuropathy diseases
  3. significant deformity of lower limb include: Modified Ashworth scale(MAS) >3; contracture, fracture, chronic joint pain.
  4. joint arthroplasty
  5. unstable vital sign
  6. can not cooperate study

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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186 participants in 2 patient groups

exercise group

Active Comparator group

Description:

elastic band strengthening exercise

Treatment:

Behavioral: elastic band strengthening exercise

exercise combine diet counseling group

Experimental group

Description:

elastic band strengthening exercise combined diet counseling.

Treatment:

Dietary Supplement: diet counseling

Behavioral: elastic band strengthening exercise