SARS-CoV-2 Associated Respiratory Failure Recovery (COVID-19 CAir)

University of Zurich (UZH)

Status: Completed

Conditions: SARS-CoV 2; COVID

Treatments: Other: Questionnaires, spirometry

Study type: Observational

Funder types: Other

Identifiers

NCT04365595

2020-00745

Details and patient eligibility

About

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the current pandemic of coronavirus disease (COVID-19) that can lead to respiratory failure requiring oxygen therapy. Some patients develop acute respiratory distress syndrome (ARDS) and may die despite intensive care therapy. Currently it is unknown a) how fast patients recover after being discharged from hospital and b) what underlying predictors may influence recovery.

Full description

Study aims:

• To evaluate subjective and objective recovery after discharge from hospital in patients with respiratory failure due to COVID-19.
• To identify risk factors for COVID-19 associated respiratory failure and prolonged recovery

Enrollment: 58 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• hospitalization at University Hospital Zurich due to COVID-19 infection
• hospital discharge max. 4 weeks ago
• requiring supplemental oxygen

Exclusion criteria

• <18 years
• non-German speaking
• no smartphone access

Trial design

58 participants in 1 patient group

SARS-CoV-2 associated respiratory failure

Description:

Participants will receive a daily HrQoL questionnaire on their personal smartphone using the docdok health application during 3 months. A selection of participants will furthermore receive a custom-built home disease monitoring device during 1 month. Both procedures start at least 4 weeks after hospital discharge.

Treatment:

Other: Questionnaires, spirometry