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SARS Cov-2 in Conjunctival Secretion in COVID-19 Patients

U

Università degli Studi dell'Insubria

Status

Completed

Conditions

Sars-CoV2
Tear

Treatments

Diagnostic Test: Tears swab

Study type

Observational

Funder types

Other

Identifiers

NCT04402853
72/2020

Details and patient eligibility

About

Observational study to evaluate the presence of SARS COV-2 in tears collected in COVID-19 patients in Lombardia region, northern Italy, and to correlate virus presence to concomitant systemic clinical conditions.

Full description

Since February 2020, Coronavirurus Disease 2019 associated to a severe acute respiratory syndrome started in China and rapidly spread all over the world and in particular in northern Italy. There are many reasons to justify this rapid diffusion in Italian Lombardia region as the high population density with more possibilities of interpersonal contact, high prevalence of respiratory pathologies, in particular in elderly people, due to pollution, high number of contacts with Chinese population for travelling and business reasons, and at last the non-windy temperate climate conditions, that increases the persistence of virus in the environment.

At now, more than eighty thousand citizens from Lombardia Region have been officially affected by the disease with a high death toll, also considering that actual numbers are certainly much underestimated.

The aim of the present study was to evaluate the prevalence of SARS COV-2 virus in tears collected from COVID-19 patients by rtPCR analysis directed to target sites of viral RNA, and to correlate virus presence to concomitant systemic clinical conditions

Enrollment

100 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Hospitalized COVID 19 patients

Exclusion criteria

  • Patients with respiratory support that interferes with tears sampling

Trial design

100 participants in 1 patient group

COVID 19 Patients
Description:
hospitalized patients with COVID 19
Treatment:
Diagnostic Test: Tears swab

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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