SBRT in the Management of Solid Spinal Metastases

Universitaire Ziekenhuizen KU Leuven

Status: Enrolling

Conditions: Spinal Metastases; Extradural Tumor

Study type: Observational

Funder types: Other

Identifiers

NCT04863612

Extradural Tumors

Details and patient eligibility

About

Documenting efficiency of SBRT in the management of epidural spinal metastases from solid tumors

Full description

The department of radiotherapy in UZLeuven recently included Stereotactic Body Radiotherapy (SBRT) in the standard of care for the management of patients with spinal metastases. The aim of this study is to prospectively document neurological outcome, performance and quality of life following surgery + SBRT for spinal metastases with imminent / actual spinal cord compression, and compare outcomes with the historical cohort of the UZLeuven patients included in the Global Spine Tumor Study Group database between 2011 and 2019 in whom prospective neurological, performance and quality of life outcomes were collected following surgery + conventional radiotherapy

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Radiological diagnosis of spinal metastasis from solid tumor with epidural imminent or actual spinal cord compression, with or without neurological deficits. Patients will be scheduled for surgery + SBRT. If contra-indications preclude surgery and only SBRT is performed, patients will still be included.
• Written informed consent to participate in the study must be obtained from the subject or proxy /legal representative
• Males and females > 18 years

Exclusion criteria

• Any concomitant condition or disease which, in the opinion of the investigator, would affect the reliability of the collected data.
• Patients that had previous radiotherapy on the index spinal level without the possibility for additional SBRT at that particular level.