SBRT Treatment for Lung Metastasis From Soft Tissue Sarcoma

Istituto Clinico Humanitas

Status

Unknown

Conditions

Metastasis From Malignant Tumor of Soft Tissues

Treatments

Radiation: Lung metastasis from soft-tissue sarcoma

Study type

Observational

Funder types

Other

Identifiers

NCT02561559

1393

Details and patient eligibility

About

In this study the investigators treat PM oligometastatic patients with SBRT. Our objective is to evaluate rate of local control of treated lesions in patients treated with Intensity Modulated Radiation Therapy (IMRT) using Volumetric Modulated Arc Therapy (VMAT) for lung metastases from STS.

Full description

The investigators started to treat PM oligometastatic patients with Stereotactic Body Radiotherapy.

The investigators objective is to evaluate rate of local control of treated lesions in patients treated with Intensity Modulated Radiation Therapy (IMRT) using Volumetric Modulated Arc Therapy (VMAT) for lung metastases from soft-tissue sarcomas. Overall and disease free survival will be evaluated as secondary endpoints.

Enrollment

37 patients

Sex

All

Ages

18 to 85 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Age 18 anni -85 years
PS according to ECOG 0-2
Histopathologically confirmation of soft tissue sarcoma
Metastatic lung lesion less than 4
Controlled primary tumor and other metastatic lesions
Metastatic lesion less than 5 such as the definition of oligometastatic patients
Written informed consent
Contraindication to surgical resection
Estimated survival ≥ 3 months
Absence of progressive disease longer than 6 months
No chemotherapy was given for at least 3 months after SBRT
Maximum diameter ≤ 5 cm