Scalp Nerve Block and Opioid Consumption in Brain Surgery

Chiang Mai University

Status and phase: Completed; Phase 4

Conditions: Brain Tumour

Treatments: Drug: Scalp block with 0.5% plain Marcaine; Drug: Scalp block with 0.9% normal saline

Study type: Interventional

Funder types: Other

Identifiers

NCT02057367

ANE2556-01510

Details and patient eligibility

About

Anterior scalp block with 0.5% plain Marcaine 20 ml. may reduce the intraoperative opioid consumption in neurosurgical patients who undergoing the supratentorial craniotomy compared to those who receive 0.9% normal saline solution (placebo).

Full description

Anterior scalp block with 0.5% plain Marcaine 20 ml. may reduce the intraoperative opioid consumption in neurosurgical patients who undergoing the supratentorial craniotomy compared to those who receive 0.9% normal saline solution (placebo).

A Prospective Randomized Double Blind Control

Enrollment: 100 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Patients who have supratentorial brain tumor
2. Patients have been scheduled to undergo an elective craniotomy to remove tumor in any surgical position
3. Patients have been general anesthetized with endotracheal intubation and control ventilation
4. Patients who have provided consent for the participation in the research and for the use of their medical record in research

Exclusion criteria

1. Pregnant patients
2. Patients who have a history of local anesthetic allergy and/ or anaphylaxis

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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100 participants in 2 patient groups, including a placebo group

Scalp block with 0.5% plain marcaine

Experimental group

Description:

Anterior scalp block with 0.5% plain Marcaine 20 ml.

Treatment:

Drug: Scalp block with 0.5% plain Marcaine

Scalp block with 0.9% normal saline

Placebo Comparator group

Description:

Anterior scalp block with 0.9% normal saline 20 ml.

Treatment:

Drug: Scalp block with 0.9% normal saline