Scalp Nerve Block on Emergence Agitation

Ajou University School of Medicine

Status and phase: Completed; Phase 4

Conditions: Agitation

Treatments: Drug: Sevoflurane; Drug: Remifentanil; Drug: Ropivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT02428283

AJIRB-MED-CT4-14-422

Details and patient eligibility

About

Emergence agitation is a common problem in children during recovery from sevoflurane anesthesia. Pain is considered as a cause of postoperative emergence agitation and compounding factor of agitation assessment in children. The purpose of this study was to investigate the effect of scalp nerve block on the emergence agitation in children undergoing nevus surgery during sevoflurane anesthesia.

Full description

Forty-four children, 1-7 years old, undergoing nevus surgery on head were enrolled. Anesthesia was induced with thiopental sodium and rocuronium, and maintained with sevoflurane. Patients were randomly assigned two groups: the control group received IV remifentanil 1 μg/kg, and the block group received scalp nerve block with 0.25% ropivacaine 2-3 ml. Time to tracheal extubation, recovery time, hemodynamic change, FLACC score, and Watcha behavior scale for emergence agitation were assessed.

Enrollment: 44 patients

Sex: All

Ages: 1 to 7 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA I-II patients undergoing general anesthesia for nevus surgery

Exclusion criteria

• developmental disorder
• neurologic disorder
• coaguloparthy
• allergy to local anesthetics

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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44 participants in 2 patient groups

Nerve block

Experimental group

Description:

Scalp nerve block was performed with 0.25% ropivacaine.

Treatment:

Drug: Ropivacaine

Drug: Sevoflurane

Control

Active Comparator group

Description:

Remifentanil was administered intravenously.

Treatment:

Drug: Remifentanil

Drug: Sevoflurane