Scandinavian Cohort Study for Optimal Use of Portal Vein Embolization

Karolinska University Hospital

Status: Unknown

Conditions: Hepatic Neoplasm

Treatments: Procedure: Portal vein embolization

Study type: Observational

Funder types: Other

Identifiers

NCT04182386

Scandinavian PVE study

Details and patient eligibility

About

Several aspects on the use of portal vein embolization (PVE) are poorly studied and todays recommendations are based on low-grade evidence. In this Scandinavian multicenter cohort study we will study some of the controversial aspects on the use of PVE to try to provide clearer answers on its optimal use. Six tertiary university hospital hepatobiliary units in Sweden, Norway and Denmark participate and contribute with all PVE procedures performed at their units during the study period. We will then study several aspects PVE technique in relation to induced hypertrophy and surgical outcome.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Right-sided PVE

Exclusion criteria

• Left-sided PVE

Trial design

300 participants in 2 patient groups

rPVE

Description:

Right portal vein embolization. All patients subjected to selective right portal vein embolization prior to planned hepatobiliary surgery.

Treatment:

Procedure: Portal vein embolization

rPVE+S4

Description:

Right portal vein embolization including segment 4 portal vein branches. All patients subjected to selective right portal vein embolization including segment 4 portal vein branches prior to planned hepatobiliary surgery.

Treatment:

Procedure: Portal vein embolization