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Scheimpflug Versus Placido-disc System in Evaluation of Corneal Higher-Order Aberrations

A

Assiut University

Status

Not yet enrolling

Conditions

Corneal Higher-order Aberrations

Treatments

Device: placido-based topographer (wavelight allegro topolyzer vario) and scheimpflug -based (Oculus Pentacam )

Study type

Observational

Funder types

Other

Identifiers

NCT06278220
Corneal HOA

Details and patient eligibility

About

Aim of work:

To assess the agreement between placido-based topographer (wavelight allegro topolyzer vario) and scheimpflug -based (Oculus Pentacam ) regard measuring corneal higher order aberrations before and after LASIK.

Full description

Higher-order aberrations (HOAs) are small optical irregularities of the eye, which can have an impact on the quality of the retinal image. In contrast to lower order aberrations, these errors cannot be corrected with regular spectacles and most contact lenses. Additionally, HOAs are responsible for an array of visual symptoms including dysphotopsia, glare, as well as a reduction in contrast sensitivity. The cornea accounts for approximately 90% of ocular aberrations.Advances and breakthroughs in wavefront aberration measurement technology can help clinicians to better understand and manage corneal higher-order aberrations (HOAs), especially for the preoperative planning of corneal refractive surgery and cataract surgery.A recent study has shown that corneal HOAs can be a sensitive parameter to differentiate early keratoconus from normal eyes. Furthermore, corneal aberrations have been widely used to evaluate dry eye and orthokeratology.LASIK surgery is widely used in the correction of refractive errors It is well known that LASIK surgery induces high-order aberrations (HOA) .The main eye element involved in the generation of such aberrations is the first corneal surface. Currently, devices based on Placido-disc, Hartmann- Shack, ray tracing, or Scheimpflug are routinely used in clinical aberration measurement. Of which Pentacam is one of common instruments that can only measure corneal aberration (including anterior and posterior corneal surface) based on Scheimpflug technology. Also Allegro Topolyzer is a Placido-based topographer that can measure anterior corneal higher order aberrations (HOAs). A better understanding of the agreement of device measurements can provide clinicians with useful information for measuring, correcting, and monitoring aberrations around refractive and cataract surgery. Investigators , therefore, aimed to study the agreement between the two instruments in anterior corneal aberration measurement.

Enrollment

36 estimated patients

Sex

All

Ages

18 to 45 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients with refractive errors from +6 diopters to -8 diopters sphere and up to -6diopters cylinder.

Exclusion criteria

  • Patients with systemic diseases such as diabetes.
  • keratoconus or keratoconus suspect, amblyopic eyes.
  • Patients with best corrected visual acuity (BCVA) not achieving 20/25.
  • glucoma
  • Previous ocular surgeries or trauma.

Trial contacts and locations

1

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Central trial contact

Naglaa MA Abdelmohsen, MD

Data sourced from clinicaltrials.gov

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