Sciatic Block Increases Regional Saturation in Peripheral Artery Occlusive Disease.

Azienda Ospedaliera Città della Salute e della Scienza di Torino

Status: Unknown

Conditions: Peripheral Artery Occlusive Disease; Popliteal Sciatic Nerve Block

Treatments: Other: Case

Study type: Observational

Funder types: Other

Identifiers

NCT04341051

0033871

Details and patient eligibility

About

We conducted Single-center prospective observational study to evaluate the improvement of peripheral vascular perfusion monitored with near-infrared spectroscopy, in patients undergoing endovascular surgery after performing sciatic nervous block.

Full description

The aims of that study is to check regional oxigen saturation variability in patients suffering from Peripheral Artery Occlusive Disease (IIa to III Fontaine classification) undergoing popliteal sciatic nerve block as analgesic procedure before vascular surgery. We want to evaluate the increase in regional microcirculation after the popliteal nerve blocks due to vasoplegic response and vasodilatation after performing regional anaesthesia. We will place NIRS electrode on the instep of the foot to evaluate regional oxigen saturation in the interested leg before the performing of popliteal sciatic nerve block and then during the surgery (after 5 minuts, 15 minuts, 30 minuts), and after the end of the procedure.

Enrollment: 31 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age: > 18 years
• Peripheral artery occlusive desease involving popliteal, tibial and/or peroneal artery
• Stadiation IIa to III in Fontaine classification
• Eligibility for PTA or Stenting

Exclusion criteria

• trophic alteration of the application site of the NIRS
• less than 18 years
• Pregnancy
• need of sedation during the procedure
• revascularization performed as emergency surgery
• Allergic reactions with local anaesthetic
• Previous surgery involving the interested artery

Trial design

31 participants in 1 patient group

Case

Description:

we will observe the regional saturation of O2 through NIRS at the following time: T0(before peripheral anesthesia); T1 (5 minutes from the block); T2 (15 minutes from the block); T3 (30 minutes from the block); T4 (after revascularization); At each interval PA, SpO2 and NIRS were also recorded in the contralateral limb as control data.

Treatment:

Other: Case