Scleral Hydrops and Intralabyrinthine Schwannoma

University Hospital, Strasbourg, France

Status: Unknown

Conditions: Hydrops Saccular

Study type: Observational

Funder types: Other

Identifiers

NCT03581396

7026

Details and patient eligibility

About

The symptoms of intralabyrinthine schwannomas (vertigo, deafness, instability, tinnitus) cut across the symptoms found in pressure pathologies involving the inner ear, particularly the endolymphatic hydrops.

Some publications have described dilatation of the membranous labyrinth (hydrops) in the presence of intralabyrinthine tumors.

It would be interesting to measure the size of the saccule (structure of the membranous labyrinth) in the presence of an intralabyrinthine schwannoma, to evaluate if some of the symptoms presented by the patients could be explained by the concomitant presence of an endolymphatic hydrops (accessible to drug therapy - Betahistine).

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria

• Age> 18,
• Subject having benefited from an exploration of internal auditory canals by MRI in our service at CHU de Hautepierre between January 1, 2008 and October 1, 2017
• Presence on the MRI of the internal auditory ducts, including the realization of a high resolution fluid sequence of FIESTA-C (exploitable) type, of an intralabyrinthine schwannoma, without extension to the internal auditory canal.
• Subject who has agreed to the use of medical data for the purposes of this research.

Criteria for Non Inclusion

• Refusal of the patient to participate in the study
• Absence of high resolution fluid sequence of fast imaging employing steady state acquisition (FIESTA-C)
• Presence of movement artifacts interfering with the interpretation of the FIESTA-C sequence
• Interior surgery of the inner ear or pontocerebellar angle, without preoperative imaging Inflammatory or infectious pathology of the concomitant middle or inner ear
• Extension of schwannoma to the internal auditory canal
• Impossibility of giving the subject informed information (difficulty understanding the subject,)
• Subject under the protection of justice
• Subject under guardianship or curatorship