ClinicalTrials.Veeva

Menu

Screening and Secondary Prevention Rheumatic Heart Disease Study (S2-RHD)

N

National Institute of Cardiovascular Diseases, Pakistan

Status

Enrolling

Conditions

Rheumatic Heart Disease

Study type

Observational

Funder types

Other

Identifiers

NCT05991219
IRB-32/2023

Details and patient eligibility

About

After basic clinical screening including history and physical, Point of care ultrasound will be performed to look at Mitral, Aortic and Tricuspid Valves for regurgitation or stenosis. For patients with confirmed Rheumatic heart disease (RHD), treatment and referral depending on stage of disease. Antibiotic prescription could be shifted to community health workers delivering preventive medications via practical clinical algorithms, diagnostic tools, availability of appropriate antibiotics, and supportive supervision. Patients will have repeat imaging at 2 years and 5 years to look at the outcome of delayed progression of valve disease.

Full description

Screening for RHD should be carried out since it is a major health concern that has been shown to have a treatable and detectable latent stage that can be diagnosed using a simple sensitive test (point of care ultrasound) and early treatment (secondary prevention using antibiotic prophylaxis) can provide a better outcome (slow progression of disease) in a cost effective way. The investigators aim to study the Incidence and Prevalence of RHD in community and school settings and aim to intervene depending on the stage the disease is picked up in.

Enrollment

5,000 estimated patients

Sex

All

Ages

10 to 30 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Rural communities in Sindh

Exclusion criteria

  • Refused to participate in the study

Trial contacts and locations

1

Loading...

Central trial contact

Sabha Bhatti, MD

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems