Screening for COVID-19 in Teachers, Childcare Educators, Pupils and Preschoolers (COKITS)

University Medicine Greifswald

Status: Completed

Conditions: SARS-CoV-2

Treatments: Diagnostic Test: Serum testing; Diagnostic Test: Nasopharyngeal swab

Study type: Observational

Funder types: Other

Identifiers

NCT04619407

BB 179/20

Details and patient eligibility

About

The main objectives of this study are

1. to establish the prevalence of SARS-CoV-2 in schools and kindergartens in the State of Mecklenburg-Vorpommern in autumn and winter 2020/2021
2. to monitor the future spread of the disease by assessing serological responses to SARS-CoV-2 in teachers and childcare educators over time

Full description

Detailed Description:

This study aims to collect information on teachers and childcare educators as well as on pupils and preschoolers in the State of Mecklenburg-Vorpommern

Over a 5 month period, 5 study visits per participant are planned. At each visit, nasal/throat swabs (for PCR testing) will be collected and participants will be asked to fill in a questionnaire (asking for SARS-CoV-2 risk factors, perceived risk, and impact of the pandemic on their quality of life). In adults, additional blood samples (for SARS-CoV-2 antibody testing) will be collected at the first and the last study visit. This will help to gain a better understanding of viral load and antibody development over time.

The remaining blood samples will be stored in a repository for future research.

The study is part of a modular SARS-CoV-2-research programme of the University Medicine Greifswald.

Enrollment: 142 patients

Sex: All

Ages: 3 to 67 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• See cohort descriptions
• Willing to have blood samples stored for future research

Exclusion criteria

• None

Trial design

142 participants in 4 patient groups

teacher

Description:

* Employed in a school in Mecklenburg-Vorpommern * Age between 18 to 67 years * Willing and able to provide informed consent * Over 5 months: Monthly nasopharyngeal swabs for SARS-CoV-2 PCR, additionally blood samples for SARS-CoV-2 antibody testing will be taken at the beginning and at the end of the study

Treatment:

Diagnostic Test: Serum testing

Diagnostic Test: Nasopharyngeal swab

pupils

Description:

* Attending school in Mecklenburg-Vorpommern * Age between 6 to 17 years * Agreement to participate * Legal representative willing and able to provide informed consent * Over 5 months: Monthly nasopharyngeal swabs for SARS-CoV-2 PCR

Treatment:

Diagnostic Test: Nasopharyngeal swab

childcare educators

Description:

* Employed in a kindergarten in Mecklenburg-Vorpommern * Age between 18 to 67 years * Willing and able to provide informed consent * Over 5 months: Monthly nasopharyngeal swabs for SARS-CoV-2 PCR, additionally blood samples for SARS-CoV-2 antibody testing will be taken at the beginning and at the end of the study

Treatment:

Diagnostic Test: Serum testing

Diagnostic Test: Nasopharyngeal swab

preschoolers

Description:

* Attending kindergarten in Mecklenburg-Vorpommern * Age between 3 to 6 years * Agreement to participate * Legal representative willing and able to provide informed consent * Over 5 months: Monthly nasopharyngeal swabs for SARS-CoV-2 PCR

Treatment:

Diagnostic Test: Nasopharyngeal swab