Screening For First Trimester's Hyperglycemia in High and Low Risk Pregnancy

Sohag University

Status: Enrolling

Conditions: Screening for Hyperglycemia in First Trimester in High and Low Risk Pregnancy

Treatments: Diagnostic Test: blood sugar

Study type: Observational

Funder types: Other

Identifiers

NCT06064552

soh-Med-23-09-04MS

Details and patient eligibility

About

Glucose intolerance is the commonest medical disorder complicating pregnancy. Hyperglycemia increases the risk of delivering a large for gestational age newborn (LGA) and related complications such as operative delivery, birth trauma and the poor adaptation of the newborn . Maternal risks of GDM include also polyhydramnios, preeclampsia, premature delivery, prolonged labor, uterine atony, postpartum hemorrhage, infection and progression of retinopathy which are the leading global causes of maternal morbidity and mortality .Detection of women at higher risk for GDM early in pregnancy is a desirable goal because interventions such as diet, medication, and exercise may be applied earlier in pregnancy and potentially can reduce later development of GDM or its associated morbidities. Most GDM cases are diagnosed after mid-gestation following an abnormal glucose challenge test (GCT). However, about 10% of patients with GDM can be diagnosed in the first trimester.

Enrollment: 100 estimated patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• • History of gestational diabetes in previous pregnancies

  • Polycystic ovaries syndrome
  • History of Macrosomic baby in previous pregnancies
  • Past history of late third trimester fetal demise
  • Past history of polyhydramnios
  • Overweight /Obese women Women diagnosed to have other endocrinopathies like suprarenal, thyroid or pituitary disorders Multi fetal pregnancies Past history of shoulder dystocia Past history of preeclampsia Family history of diabetes

In addition, a comparable group of low-risk women will be included like primigravida healthy women or those with normal obstetric history.

Exclusion criteria

• all patient not have thev inclusion criteria

Trial design

100 participants in 2 patient groups

high risk pregnancy

Description:

Pregnant women with history of gestational diabetes in previous pregnancies, Polycystic ovaries syndrome, history of Macrosomic baby in previous pregnancies, Past history of late third trimester fetal demise, Past history of polyhydramnios, Overweight /Obese women, Women diagnosed to have other endocrinopathies like suprarenal, thyroid or pituitary disorders, multi fetal pregnancies, Past history of shoulder dystocia, Past history of preeclampsia

Treatment:

Diagnostic Test: blood sugar

low risk pregnancy

Description:

average risk population like primigravida healthy women or those with normal obstetric history.

Treatment:

Diagnostic Test: blood sugar