Screening for GDM in Women With PCOS and Controls

Odense University Hospital

Status: Completed

Conditions: Gestational Diabetes Mellitus; Polycystic Ovary Syndrome

Treatments: Other: OGTT by indication; Other: OGTT by randomization

Study type: Interventional

Funder types: Other

Identifiers

NCT02183558

GDM OBK

Glucose OBK (Other Identifier)

Details and patient eligibility

About

Women with polycystic ovary syndrome (PCOS) are often insulin resistant. During pregnancy, insulin sensitivity decreases. The investigators examine glucose metabolism during oral glucose tolerance test and the incidense of gestational diabetes mellitus in a prospective cohort of pregnant women with PCOS and controls.

Enrollment: 2,500 patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Pregnancy achieved during 2010-2012
• Residents of the municipality of Odense

Exclusion criteria

• Moving from Odense during pregnancy

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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2,500 participants in 2 patient groups

OGTT by randomization

Experimental group

Description:

Women without risk factors for GDM are offered OGTT in gestational week 28

Treatment:

Other: OGTT by randomization

OGTT by indication

Experimental group

Description:

Women with risk factors for OGTT are offered diagnostic 2 hour OGTT in pregnancy week 28

Treatment:

Other: OGTT by indication