Search for Biomarkers in Human Glaucoma: Lymphocytes Alterations and Rate of Progression

University of Parma

Status: Completed

Conditions: Glaucoma, Open-Angle

Study type: Observational

Funder types: Other

Identifiers

NCT00981422

PARMABIOMARKERS001

Details and patient eligibility

About

The aim of this study was to evaluate the lymphocyte phenotype in primary open- angle glaucoma (POAG) patients compared to healthy subjects of the same age, in order to confirm the importance of immune responses in glaucoma and the possible correlation to the severity of the disease.

Enrollment: 40 patients

Sex: All

Ages: 19 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of primary open-angle glaucoma
• age between 19 an 85 years old

Exclusion criteria

• age less than 19 or more than 85 yrs
• positive history for (a) neurodegenerative diseases, (b) autoimmune diseases, (c) cancer, (d) viral infection and (e) diabetes, (f)systemic inflammation

Trial design

40 participants in 2 patient groups

Glaucoma patients

Description:

POAG patients selected by an ophthalmologist from the Glaucoma Service, Ophthalmology Institute, University of Parma

Healthy

Description:

healthy subjects with negative history for (a) neurodegenerative diseases, (b) autoimmune diseases, (c) cancer, (d) viral infection, (e) diabetes, and (f) systemic inflammation