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Search of Protein Biomarkers in Order to Achieve a Molecular Classification of Gliomas (GLIOMIC)

U

University Hospital, Lille

Status

Completed

Conditions

Glioblastoma

Study type

Observational

Funder types

Other

Identifiers

NCT02473484
2013_27
2014-A00185-42 (Other Identifier)

Details and patient eligibility

About

The aim is to classify high grade glioma by matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI). In order to provide more specific informations for the diagnosis and the prognosis of high grade glioma.

Enrollment

78 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Main inclusion criteria:

  • Patients with grade III or IV glioma newly diagnosed with histological evidence
  • Surgical indication
  • Tumor tissue available at biobank of Lille
  • Men and women aged ≥ 18 years
  • Informed Consent signed by the patient or his legal representative.

Main exclusion criteria:

  • Antecedents of other cancers except basal cell skin cancer or carcinoma in situ of the uterus cervix
  • Previous history of brain radiotherapy
  • Anti-tumor systemic treatments (chemotherapy or targeted therapy) prior to surgery of glioma
  • Genetic disease that may cause brain tumor, potentially radiation-induced tumor
  • History of degenerative neurological disease prior to diagnosis
  • contraindication to MRI

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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