Secondary Cancer Risk After Radiation Therapy for Rectal Cancer

Kantonsspital Graubuenden

Status: Completed

Conditions: Neoplasms, Second Primary

Treatments: Other: No intervention in this retrospective study

Study type: Observational

Funder types: Other

Identifiers

NCT02572362

KEK-ZH-Nr. 2014-0255

Details and patient eligibility

About

Retrospective study comparing dose distribution of 3D conformal radiotherapy (3DCRT) and volumetric-modulated arc therapy (VMAT) to estimate secondary cancer risk for patients having had radiation therapy for rectal cancer. Twenty-five patients are included in this study. Planning CT scans are used for comparison of dose distribution and calculation of second cancer risk.

Full description

A model-based Analysis calculating the organ-specific excess lifetime attributable risk using the planning CT data sets of 25 patients to estimate second cancer risk for patients after radiotherapy for rectal cancer comparing conventional 3DCRT with VAMT techniques.

Enrollment: 25 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male/Female > 18 years of age
• pre or postoperative radiation therapy for rectal cancer
• Planning CT

Exclusion criteria

• Planning CT not available