Sedation and Postoperative Cognitive Functions

Izmir Ataturk Training and Research Hospital

Status: Completed

Conditions: Femoral Fractures; Cognitive Impairment

Study type: Observational

Funder types: Other

Identifiers

NCT05737459

IAERH

Details and patient eligibility

About

Patients over the age of 65 who underwent elective surgery for a hip fracture and were sedated during spinal anesthesia were included in the study. Patients who were given ketamine and dexmedetomidine for sedation were included in the study. The Mini Mental Status Tests of the patients measured on the first and third days of the operation in the preoperative period were determined from the hospital records and recorded.

Full description

Patients over the age of 65 who underwent elective surgery for a hip fracture and were sedated during spinal anesthesia were included in the study. The cognitive functions of these patients, which were evaluated by a Mini-Mental Test in the preoperative period, on the first and third days of surgery, were recorded from routine patient follow-up forms.

Sedation scores of the patients evaluated by Intraoperative Alertness/Sedation Scale (OAA/S) Observer Evaluation were recorded. Intraoperative hemodynamic data were recorded. The interventions applied to the patient were performed by anesthesiologists who were not involved in the study according to their preferences as part of the routine. The researchers were not involved in any intervention performed on the patient, only the data were recorded.

Enrollment: 82 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients over the age of 65 who underwent surgery under spinal anesthesia due to hip fracture
• Volunteered to participate in the study

Exclusion criteria

• Patients who are under the age of 65
• Patients with known histories of dementia
• Patients with Alzheimer's disease
• Patients with central nervous system disease
• Patients who scored 15 or less according to the Mini Mental Status Test (MMSE)
• Patients who underwent surgery under general anesthesia
• Patients who refused to voluntarily participate in the study

Trial design

82 participants in 2 patient groups

Group K

Description:

Those who have been administered ketamine for perioperative sedation

Group D

Description:

Those who have been administered dexmedetomidine for perioperative sedation.