Sedentary Behavior Breaks With Isometric Exercise in Cardiovascular Health Indicators (BREAK001)

University of Nove de Julho

Status: Completed

Conditions: Sedentary Behavior

Treatments: Other: Leg Extension Isometric Training

Study type: Interventional

Funder types: Other

Identifiers

NCT03949205

BREAK001

Details and patient eligibility

About

The goal of this study is to analyze the chronic effects of sedentary behavior breaks using the leg extension isometric exercise in the cardiovascular health indicators of healthy adults exposed to prolonged time in the sitting position. The patients recruited will be randomized into two groups: leg extension isometric training (TIE) and control group (CG). The TIE group will perform 12 weeks of isometric training. The CG will be advised not to change their routine activities, especially diet and physical activities.In the pre and post-intervention periods cardiovascular measures will be obtained.

Full description

Long periods in sedentary behavior promote deterioration of vascular function, which is directly associated with the occurence of chronic noncommunicable diseases. In this context, the execution of interruptions in this behavior (breaks) is recommended. Studies have shown benefits of isometric training in vascular function, which could be useful to minimize the consequences of time spent in sedentary behavior. Thus, the goal of this study is to analyze the chronic effects of sedentary behavior breaks using leg extension isometric exercise in the cardiovascular health indicators of adults exposed to prolonged time in the sitting position. The target population of the study will consist of healthy subjects above 18 years of age of both genders. All subjects will be submitted to measurements of endothelial function, blood pressure and cardiac autonomic modulation. After these measurements, the subjects will be randomized into two groups: leg extension isometric training group (TIE) and control group (CG). After 12 weeks both groups will be submitted to the same measurements from pre-intervention.

Enrollment: 17 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• No diagnostic of cardiovascular diseases or diabetes
• Do not present high cardiovascular risk
• Do not participate in an exercise program in the previous six months
• Occupational activity that requires more than six hours of sitting time per day
• Do not be a smoker or make use of medications

Exclusion criteria

• Adherence to the training sessions inferior to 85%
• Adherence to another supervised exercise program
• Change the characteristics of the occupational activities

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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17 participants in 2 patient groups

Leg Extension Isometric Training

Experimental group

Description:

Experimental group will perform leg extension isometric exercise.

Treatment:

Other: Leg Extension Isometric Training

Control Group

No Intervention group

Description:

Control group will be advised to maintain their work habits and not to change their routine activities, especially diet and physical activities.