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Segment IV Hypertrophy After Liver Venous Deprivation

University Hospital Center (CHU) logo

University Hospital Center (CHU)

Status

Completed

Conditions

Major Hepatectomy

Study type

Observational

Funder types

Other

Identifiers

NCT04370132
RECHMPL20_0212

Details and patient eligibility

About

before major hepatectomy, in case of insufisant future liver remanent volume or function, portal embolization is a routinely used method to enable growth of the future liver remnant. Recently liver venous deprivation has been described in some pioneer centre. The results are processing with greater and faster hypertrophy allowing probably less drop out from the embolization to surgery compared to portal embolization.

In major hepatectomy, and specially in right or extended right hepatectomy the segment IV plays an important role in the proportion of future liver remnant.

Despite the growing interest in the scientific community for liver venous deprivation many aspects concerning the liver hypertrophy remains unexplored. In particular the the degree of hypertrophy of segment IV after liver venous deprivation compared to portal embolization.

Enrollment

40 patients

Sex

All

Ages

18 to 100 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • patient with liver tumor selected for right hepatectomy with insufficient future liver remnant who have undergoes portal embolization or liver venous deprivation

Exclusion criteria

  • left / extended left hepatectomy

Trial design

40 participants in 2 patient groups

Group of patient with liver venous deprivation
Description:
Group of patient with liver venous deprivation
Group of patient with portal embolization
Description:
Group of patient with portal embolization

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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