Self-Administered Transcranial Direct Current Stimulation for Pain in Older Adults With Knee Osteoarthritis

Florida State University

Status

Completed

Conditions

Osteo Arthritis Knee

Treatments

Device: Sham tDCS

Device: Active tDCS

Study type

Interventional

Funder types

Other

NIH

Identifiers

NCT04016272

HSC-SN-19-0469

R15NR018050 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The purpose of this study is to assess the feasibility, acceptability, and efficacy of self-administered transcranial direct current stimulation (tDCS) in older adults with knee osteoarthritis (OA)

Enrollment

123 patients

Sex

All

Ages

50 to 85 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

have symptomatic knee OA based on American College of Rheumatology Clinical criteria
have had knee OA pain in the past 3 months with an average of at least 30 on a 0-100 NRS for pain
can speak and read English
have no plan to change medication regimens for pain throughout the trial

Exclusion criteria

prosthetic knee replacement or nonarthroscopic surgery to the affected knee
history of brain surgery, brain tumor, seizure, stroke or intracranial metal implantation
systemic rheumatic disorders, including rheumatoid arthritis, systemic lupus erythematosus, and fibromyalgia
alcohol/substance abuse
current use of sodium channel blockers, calcium channel blockers and NMDS receptor antagonists
diminished cognitive function that would interfere with understanding study procedures(i.e., Mini-Mental Status Exam score ≤ 23)
pregnancy or lactation
hospitalization within the preceding year for psychiatric illness
no access to a device with internet access that can be used for secure videoconferencing for real-time remote supervision