SELF-BREATHE RCT for Chronic Breathlessness

King's College Hospital NHS Trust

Status: Completed

Conditions: Bronchiectasis Adult; Post COVID-19; Sickle Cell Disease; Cancer; Interstitial Lung Disease; Asthma; Dyspnea; Renal Failure; Chronic Heart Failure; Liver Failure; Cystic Fibrosis; COPD

Treatments: Other: SELF-BREATHE

Study type: Interventional

Funder types: Other

Identifiers

NCT04574050

20/LO/1108 (Other Identifier)

IRAS 285303

Details and patient eligibility

About

A feasibility RCT comprising two groups:

1. Intervention (SELF-BREATHE in addition to standard NHS care)
2. Control group (standard / currently available NHS care)

Enrollment: 52 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults ≥ 18 years of age, with the ability to read and type in English
• Access to a computer, or tablet or smart phone, with internet access and the ability to email
• Chronic breathlessness (CB) defined as; breathlessness that persists (>3months) despite optimal pharmacological treatment of the underlying disease including cancer, chronic obstructive pulmonary disease (COPD),asthma, interstitial lung disease (ILD), bronchiectasis, cystic fibrosis (CF) chronic heart failure (CHF), sickle cell disease, chronic renal/ liver failure or post COVID-19
• Chronic breathlessness at rest or on exertion; MRC dysponea score >2
• Willing to engage with short-term self-guided internet-based breathlessness intervention (SELF-BREATHE)
• Able to provide informed consent

Exclusion criteria

• Breathlessness of unknown cause
• A primary diagnosis of chronic hyperventilation syndrome
• Currently participating in a rehabilitation programme, e.g. pulmonary/cardiac rehabilitation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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52 participants in 2 patient groups

SELF-BREATHE

Experimental group

Description:

Access to a self -guided, internet -based intervention for patients with chronic breathlessness known as SELF-BREATHE

Treatment:

Other: SELF-BREATHE

Control

No Intervention group

Description:

standard / currently available NHS care