Self-management of Anticoagulation Treatment

University of Bergen

Status: Completed

Conditions: Venous Thromboembolism; Atrial Fibrillation; Artificial Heart Valve

Treatments: Other: Training

Study type: Interventional

Funder types: Other

Identifiers

NCT02864537

Lokkebo

Details and patient eligibility

About

The aim of the study was to compare self-management of anticoagulant treatment with conventional anticoagulant treatment in Norway.

Full description

Patients (n=132) on anticoagulant treatment with warfarin participated in a 21 weeks training program where they learned how to analyse International Normalised Ratio (INR) using the point-of-care instrument CoaguChek®XS and dose warfarin. The patients had to display their skills through a test before considered self-managing. They continued to measure INR weekly for two years. All INR values during the training program and self-control period were collected. In addition, the patients were told to notify if they had any complications during this period. INR values and complications two years before enrolment was collected from INR cards and/or their general practioner. The participant filled in a quality of life-questioner at enrolment and after two years of self-management.

Enrollment: 130 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• On life-long oral anticoagulation therapy
• Judged to be qualified for patient self-management anticoagulation treatment by their GP
• Motivated to follow the training program

Exclusion criteria

• Drug abuse
• Liver disease

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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130 participants in 2 patient groups

Conventional treatment

No Intervention group

Description:

Conventional anticoagulation treatment Before enrolment

Self-management

Experimental group

Description:

Trained to monitor INR and dose warfarin

Treatment:

Other: Training