Seminal Levels of PGK2 and ACRV1 as Predictors of Micro-TESE Results in NOA

Assiut University

Status: Not yet enrolling

Conditions: Male Infertility Due to Azoospermia

Treatments: Diagnostic Test: Measurement of PGK2 and ACRV1 levels in the semen of infertile males undergoing testicular sperm extraction (TESE).

Study type: Observational

Funder types: Other

Identifiers

NCT06307639

MYMSwifee

Details and patient eligibility

About

• Measurement of PGK2 and ACRV1 levels in the semen of infertile males undergoing testicular sperm extraction (TESE).
• Correlate seminal levels of PGK2 and ACRV1 with sperm retrieval results and histopathology analysis of testicular biopsy samples.

Enrollment: 64 estimated patients

Sex: Male

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Infertile males with normal volume, functional (non-obstructive) azoospermia.
• Age: 18-45 years

Exclusion criteria

• Patients with proven obstructive azoospermia.
• Cryptorchidism.
• Testicular Agenesis and testicular atrophy.
• Patient with exposure to gonadal toxins like chemotherapy, radiotherapy, and alkylating agents.