Semitendinosus Graft as Meniscal Transplant

Karolinska Institute

Status: Enrolling

Conditions: ACL; Graft Failure; Meniscus Tear; Patient Satisfaction; Osteo Arthritis Knee

Treatments: Procedure: Surgical technique

Study type: Observational

Funder types: Other

Identifiers

NCT04753424

semiTmeniscus

Details and patient eligibility

About

Removal of meniscal tissue is described to result in poor knee function and a significant risk for future development of osteoarthritis. Different implants have been suggested to substitute a removed meniscus. Meniscal allograft transplantation is not widely available due to costs and availability. The semitendinosus tendon is a known graft with biological properties with potential to remodel and revascularize in an intraarticular environment such as anterior cruciate ligament reconstruction. The objective for this study was to investigate whether the semitendinosus tendon graft could function as a meniscal transplant.

Enrollment: 10 estimated patients

Sex: All

Ages: 20 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Previous subtotal or total meniscectomy
• Post meniscectomy symptoms
• No osteoarthritic changes on radiography more than Ahlbäck 1
• Knee aligment (hip-knee-angle) +/- 3°
• No persisting ACL insufficiency

Exclusion criteria

• Difficulty understanding the instructions
• Current psychiatric diagnosis
• Smoking

Trial design