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Senior-COVID-Rea Multicentric Survey (SeniorCOVIDRea)

Civil Hospices of Lyon logo

Civil Hospices of Lyon

Status

Unknown

Conditions

COVID-19 Disease, Severe Form

Treatments

Other: Group1

Study type

Observational

Funder types

Other

Identifiers

NCT04422340
69HCL20_0386

Details and patient eligibility

About

With the spread of COVID-19 epidemic since 2019 in Wuhan, China health plans have to be adapted continuously in response to the emergency. The first publications from the Chinese experience demonstrate an increase in the incidence of COVID-19 infections in patients over 60 years of age, a higher frequency of severe forms of the disease and therefore theoretical indications of orientation towards resuscitative care.

However, the first published data from Hubei province suggest a low benefit of resuscitation for patients between 70 and 80 years of age and null in patients over 80 years of age. These data question the individual benefit / risk balance of an orientation towards resuscitation for this category of patients, their quality of life and the concept of unreasonable obstinacy.

Among the covariates associated with resuscitation mortality described in the data published to date, cardiovascular comorbidities, certain biological covariates (LDH, creatinine, lymphocytes, neutrophils, TP, D-dimers, etc.), the time between the first symptoms and the entry into resuscitation have been identified.

The objective of this multicentric observational study is to determine the clinical and biological covariates predictive of mortality in the population of patients over 60 years of age admitted in intensive care unit, in particular by integrating functional and nutritional data from patients 1 month before COVID-19 infection.

Enrollment

185 estimated patients

Sex

All

Ages

60+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patient over 60
  • sent to the intensive care unit
  • whose COVID diagnosis has been established (RT-PCR and / or chest scanner)

Exclusion criteria

  • Refusal of the patient or his support person to participate in the study

Trial contacts and locations

7

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Central trial contact

Claire Falandry, MD

Data sourced from clinicaltrials.gov

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