Sensitivity and Specificity of Aridol Challenge for a Diagnosis of Asthma by a Specialist Pulmonologist

St. Olavs Hospital

Status: Terminated

Conditions: Asthma

Study type: Observational

Funder types: Other

Identifiers

NCT00491153

2006-006469-17 (Other Identifier)

4.2006.3606(REK)

Details and patient eligibility

About

The purpose of this study is to estimate the sensitivity, specificity and positive and negative predictive values of a positive Aridol challenge with respect to a specialist pulmonologist diagnosis of asthma in corticosteroid naive subjects with asthma-like symptoms and no previous diagnosis of asthma. The comparator is methacholine provocation

Enrollment: 35 patients

Sex: All

Ages: 16 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Informed consent
• Provisional or possible asthma diagnosis
• FEV1 at least 70% of predicted at inclusion

Exclusion criteria

• Contraindications for bronchial provocation challenge or spirometry
• Respiratory tract infection within previous 6 weeks
• Significant co-morbidity
• > 10 pack year smoking history
• Other lung diseases
• Pregnancy, lactation