Sensitivity of Multiparametric MRI in Differentiation Between Muscle Invasive and Non-muscle Invasive Urinary Bladder Cancer

H

Helwan University

Status

Completed

Conditions

Cancer, Bladder

Treatments

Procedure: diagnostic cystoscopy +/- TURBT
Radiation: multiparametric MRI on the bladder

Study type

Observational

Funder types

Other

Identifiers

NCT05324033
REC-FMHU 51/2021

Details and patient eligibility

About

Differentiation between non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC) is a cornerstone in the treatment plans.Therefore, this study will try to evaluate the sensitivity and reliability of mpMRI in accurate diagnosis of cancer bladder. Primary objective: to detect the sensitivity of multiparametric MRI in differentiation between muscle Invasive and non-muscle invasive Urinary Bladder Cancer in relation to the conventional cystoscopy and histopathological examination of the biopsy.

Enrollment

30 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • All patients diagnosed with NMIBC or MIBC during diagnostic cystoscopy or by any radiologic investigation in the Urology department of Helwan university hospitals without being restricted to age or sex.
  • All histological types of bladder cancer
  • Newly diagnosed, recurrent cases, or even patients undergoing follow-up cystoscopy.

Exclusion criteria

  • Patients with elevated renal function according to their age as this will be a contraindication to DCE MRI.
  • Patients with absolute contraindication to MRI (e.g.: metallic prosthesis).
  • Patients with contraindication to undergo TURBT (e.g.: unfit for surgery).

Trial design

30 participants in 2 patient groups

muscle invasive cancer bladder
Treatment:
Radiation: multiparametric MRI on the bladder
Procedure: diagnostic cystoscopy +/- TURBT
non-muscle invasive cancer bladder
Treatment:
Radiation: multiparametric MRI on the bladder
Procedure: diagnostic cystoscopy +/- TURBT

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems