Sensitivity of Multiparametric MRI in Differentiation Between Muscle Invasive and Non-muscle Invasive Urinary Bladder Cancer

Helwan University

Status

Completed

Conditions

Cancer, Bladder

Treatments

Procedure: diagnostic cystoscopy +/- TURBT

Radiation: multiparametric MRI on the bladder

Study type

Observational

Funder types

Other

Identifiers

NCT05324033

REC-FMHU 51/2021

Details and patient eligibility

About

Differentiation between non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC) is a cornerstone in the treatment plans.Therefore, this study will try to evaluate the sensitivity and reliability of mpMRI in accurate diagnosis of cancer bladder.

Primary objective: to detect the sensitivity of multiparametric MRI in differentiation between muscle Invasive and non-muscle invasive Urinary Bladder Cancer in relation to the conventional cystoscopy and histopathological examination of the biopsy.

Enrollment

30 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

All patients diagnosed with NMIBC or MIBC during diagnostic cystoscopy or by any radiologic investigation in the Urology department of Helwan university hospitals without being restricted to age or sex.
All histological types of bladder cancer
Newly diagnosed, recurrent cases, or even patients undergoing follow-up cystoscopy.

Exclusion criteria

Patients with elevated renal function according to their age as this will be a contraindication to DCE MRI.
Patients with absolute contraindication to MRI (e.g.: metallic prosthesis).
Patients with contraindication to undergo TURBT (e.g.: unfit for surgery).