Sensitivity to Ovarian Hormones and Depression in Adolescents (SOHDA)

University of Calgary

Status

Begins enrollment this month

Conditions

Depressed

Study type

Observational

Funder types

Other

Identifiers

NCT07317895

REB25-1647

Details and patient eligibility

About

The goal of this observational study is to learn about the relationship between changes in ovarian hormones (estrogen and progesterone) and adolescent depression. The main question it aims to answer is:

Can we identify a subset adolescents assigned female at birth with a history of depression who are particularly sensitive to changes in ovarian hormones? Participants will be monitoring daily absolute ovarian hormone levels at home using the Mira Analyzer and answer online survey questions about their mental health for 90 days.

Enrollment

94 estimated patients

Sex

Female

Ages

12 to 18 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Assigned female at birth, at least 1 year post-menarche, naturally cycling, history of depression or symptoms of depression, and able to read and write in English.

Exclusion criteria