Sensory Interaction and Balance Control During Standing and Walking in Healthy Young and Older Adults

Hasselt University

Status: Not yet enrolling

Conditions: Older Adults (65 Years and Older); Young Adults; Healthy; Elderly

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT06629922

HasseltU100

Details and patient eligibility

About

This project is designed to: a) develop a new test called UHasselt Locomotor Sensory Integration Test (UHLSINT) which would allow us to evaluate sensory interaction process in locomotion assess whether Locomotor CTSIB and to investigate whether UHLSINT is a reliable test to evaluate sensory interaction in both young and older adults, b) evaluate the difference in sensory interaction and balance performance between standing and walking between both young and older adults, c) examine the changes in sensory interaction process under challenging conditions such as perturbations, dual-task, and when both are present between both young and older adults, d) examine the association between overall fall risk defined by the single-large perturbations and sensory interaction processes used during all the trials in both age groups.

In order to achieve these aims, 10 trials will be conducted:

Trial 1- Single-Large Perturbation in Standing Trial 2- Single-Large Perturbation in Walking Trial 3- Instrumented CTSIB Trial 4- Locomotor CTSIB Trial 5- Instrumented CTSIB + Perturbations Trial 6- Locomotor CTSIB + Perturbations Trial 7- Instrumented CTSIB + Auditory Stroop Test Trial 8- Locomotor CTSIB + Auditory Stroop Test Trial 9- Instrumented CTSIB + Perturbations + Auditory Stroop Test Trial 10- Locomotor CTSIB + Perturbations + Auditory Stroop Test

Two different treadmill perturbations will be applied in addition to the Instrumented CTSIB and UHLSINT: a) slip perturbations, b) continuous perturbations. An auditory stroop task will be applied in relevant trials.

All of the trials will be performed in CAREN High-End Systems (Motek Medical BV, Amsterdam, The Netherlands) which is a motion capture system that is equipped with a treadmill mounted on a 6 degree of freedom motion base, a 360º dome-shaped virtual reality (VR) screen, and a marker-based movement analysis system.

Enrollment: 64 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Young adults who: a) aged between 18 to 35 years old and, b) have never been diagnosed with somatosensory, visual, and vestibular deficits as reported by the participants, will be invited to participate. Community-dwelling older adults who: a) are 65 years old and over and, b) have not fallen in the last 12 months will also be invited to participate.

Exclusion criteria

• having had serious lower extremity injuries or operations in the past year,
• having any neurological (stroke, epilepsy, Parkinson's disease, etc.), sensory (i.e. peripheral neuropathy, diminished sense of pain, etc.) or motor disorder that can interfere with the results of the study
• Diagnosed vascular, respiratory, cardiac, orthopedic, or other disorders that affect the subject's ability to exercise safely,
• Medication affecting exercise tolerance. Additionally, based on the CAREN High-End Systems contraindications and risk factors the following exclusion criteria will be applied to the participants: a) a body weight higher than the 135 kg, b) an inability to properly adjust the harness to the respective body part due to pregnancy, colostomy bags, skin lesions that cannot be protected appropriately and any other reason that prevents a proper, pain-free adjustment of the harness.

Trial design

64 participants in 2 patient groups

Young Adults

Description:

a) aged between 18 to 35 years old and, b) have never been diagnosed with somatosensory, visual, and vestibular deficits as reported by the participants

Treatment:

Other: No intervention

Older Adults

Description:

a) are 65 years old and over and, b) have not fallen in the last 12 months will also be invited to participate

Treatment:

Other: No intervention