Sensory Properties of Bowel Cleansing Solutions

American University of Beirut Medical Center

Status: Completed

Conditions: Laxative Bowel Cleansing Solutions

Treatments: Behavioral: acceptability test; Behavioral: Descriptive analysis

Study type: Interventional

Funder types: Other

Identifiers

NCT02642783

NUT.AO.19

Details and patient eligibility

About

Samples of 4 commercially available bowel cleansing solutions, namely PEG-electrolyte + ascorbic acid (PEG-Asc, Moviprep®, Norgine, UK), PEG-electrolyte (PEG, Fortrans® Ibsen, France), sodium picosulfate/magnesium citrate (SPS, Picoprep®, Ferring, Switzerland), and oral sodium sulfate (OSS, Izinova®, Ibsen, France) were prepared according to the manufacturer's instructions. Descriptive analysis was conducted with trained panelists (N= 14) to create a sensory profile for the solutions and generated attributes were rated on an unstructured 15-cm line scale using the Compusense at-hand® (Guelph, Canada) sensory evaluation software. Acceptability testing was carried out with untrained participants (N=80) and samples were rated on the 9-point hedonic scale. Moreover, a Just-About-Right (JAR) scale was included for the four basic tastes to determine their compatibility with optimum taste/acceptability levels in the products.

Enrollment: 14 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age between 18 and 50 years

Exclusion criteria

• allergies to polyethelene glycol (PEG), artificial sweeteners

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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14 participants in 2 patient groups

Descriptive analysis

Other group

Description:

panelists were asked to rate different sensory attributes for different laxative bowel cleansing solutions on a 15 cm line scale.

Treatment:

Behavioral: Descriptive analysis

Acceptability test

Other group

Description:

panelists were asked to rate the acceptability of different laxative bowel cleansing solutions using the 9-point hedonic scale.

Treatment:

Behavioral: acceptability test