Seoul National University Pituitary Disease Cohort Study (SNU-PIT)

Seoul National University

Status: Enrolling

Conditions: Pituitary Stalk Compression Hyperprolactinaemia; Central Diabetes Insipidus; Cushing's Disease; Pituitary Incidentaloma; Prolactinoma; Acromegaly; Pituitary Tumor; Pituitary Disease

Treatments: Other: Dynamic hormone study and Magnetic resonance imaging

Study type: Observational

Funder types: Other

Identifiers

NCT03474601

1503-040-654

Details and patient eligibility

About

The purpose of this study is to investigate the treatment and natural history of pituitary disease. We have a longstanding interest in pituitary disease including acromegaly, central diabetes insipidus, and nonfunctioning pituitary adenoma. We will continue to follow patients and recruit new patients for treatment and follow-up. Blood and pituitary tumor tissue (when available through clinical care) will be saved for future analyses related to pituitary disease.

Full description

Subjects for this study will be recruited if they are:

1. Adults, male or female aged 18 years or older
2. Have been diagnosed with pituitary diseases

Enrollment: 1,600 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subjects for this study will be recruited if they are:

  1. Adults, male or female aged 18 years or older
  2. diagnosed with pituitary diseases such as acromegaly, Cushing's disease, hyperprolactinemia, nonfunctioning pituitary adenoma, pituitary stalk lesions, central diabetes insipidus, and craniopharyngiomas

Exclusion criteria

• Patients who do not agree with the study

Trial design

1,600 participants in 8 patient groups

Acromegaly

Description:

Patients diagnosed with acromegaly

Treatment:

Other: Dynamic hormone study and Magnetic resonance imaging

Cushing's disease

Description:

Patients diagnosed with Cushing's disease

Treatment:

Other: Dynamic hormone study and Magnetic resonance imaging

Hyperprolactinemia/prolactinomas

Description:

Patients diagnosed with hyperprolactinemia/prolactinoma

Treatment:

Other: Dynamic hormone study and Magnetic resonance imaging

Pituitary stalk lesions

Description:

Patients diagnosed with pituitary stalk lesions

Treatment:

Other: Dynamic hormone study and Magnetic resonance imaging

Nonfunctioning pituitary adenomas

Description:

Patients diagnosed with nonfunctioning pituitary adenomas

Treatment:

Other: Dynamic hormone study and Magnetic resonance imaging

Central diabetes insipidus

Description:

Patients diagnosed with central diabetes insipidus

Treatment:

Other: Dynamic hormone study and Magnetic resonance imaging

Craniopharyngioma

Description:

Patients diagnosed with craniopharyngiomas

Treatment:

Other: Dynamic hormone study and Magnetic resonance imaging

Others

Description:

Patients diagnosed with other suprasellar/parasellar lesions

Treatment:

Other: Dynamic hormone study and Magnetic resonance imaging