Separation Versus Integrated Approach in Combining ECMO With CRRT

C

Chulalongkorn University

Status

Enrolling

Conditions

AKI

Treatments

Device: Combination of extracorporeal membrane oxygenation and continuous renal replacement therapy

Study type

Observational

Funder types

Other

Identifiers

NCT05036616
IRB.151/64

Details and patient eligibility

About

This investigation aims to evaluate the filter life time of CRRT membrane and complication of combining ECMO and CRRT.

Enrollment

40 estimated patients

Sex

All

Ages

18 to 90 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • > 18 years
  • Refractory acidosis (pH<7.2 or HCO3<15)
  • Refractory volume overload
  • Refractory hyperkalemia (K>6.2mEq/L or EKG change)
  • Anuria or oliguria (urine output <0.5 mL/kg/hr for 6-12hr)
  • High BUN >100 mg/dL or uremic symptom
  • Increase intracranial pressure

Exclusion criteria

  • Pregnancy
  • Not use heparin in ECMO
  • Chronic kidney disease with CRRT
  • AKI with Glomerulonephritis, Interstitial nephritis, Vassculitis or Urinary tract obstruction

Trial design

40 participants in 2 patient groups

Separation technique
Treatment:
Device: Combination of extracorporeal membrane oxygenation and continuous renal replacement therapy
Integration technique
Treatment:
Device: Combination of extracorporeal membrane oxygenation and continuous renal replacement therapy

Trial contacts and locations

0

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Central trial contact

Sasipha tachaboon

Data sourced from clinicaltrials.gov

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