Sequential Intravesical Gemcitabine and Docetaxel for Rescue Therapy in BCG Unresponsive Non-muscle Invasive Bladder Cancer Patients

Dokuz Eylül University (DEU)

Status: Not yet enrolling

Conditions: Docetaxel; Bladder Cancer; Intravesical Instillation; Gemcitabine; BCG

Treatments: Drug: Intravesical Solution

Study type: Observational

Funder types: Other

Identifiers

NCT06374914

TUO-UR-23-05

Details and patient eligibility

About

Studies in the literature are limited both throughout Turkey and in general. For this reason, as a result of the study that we will create, it will provide us with information for bladder protective treatments in patients who do not respond to BCG therapy in bladder cancer patients.

Enrollment: 120 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• BCG refractory/relapsed/unresponsive or intolerant Who do not want or are not suitable for radical cystectomy

Exclusion criteria

• BCG naive A history of multiple cancers Having a radical cystectomy plan

Trial design

120 participants in 2 patient groups

Patients with BCG unresponsiveness and receiving intravesical gemcitabine doxetaxel

Treatment:

Drug: Intravesical Solution

Patients with BCG unresponsiveness and radical cystectomy performed