Serial Progesterone Level Measurements During the Menstrual Cycle in Subfertile Women

Turgut Aydın

Status: Unknown

Conditions: Subfertility, Female; Ovulation Disorder

Treatments: Diagnostic Test: Serum progesterone levels

Study type: Observational

Funder types: Other

Identifiers

NCT05211583

Progesterone

Details and patient eligibility

About

Ovulatory dysfunction is identified in 15% of all infertile couples and it accounts for 40% of female infertility. Ovulatory dysfunction may be more subtle in women with regular menses. Detecting the day of ovulation is necessary for optimizing natural conception, diagnosis of cycle disturbances and also timing for embryo transfer in natural cycle frozen-thawed embryo transfers. In order to diagnose ovulatory dysfunction, ovulation physiology and change of reproductive hormones during the menstrual cycle should be understood. In the present study we aimed to evaluate serial serum hormonal cut-off levels referenced to ovulation in subfertile women with regular menses.

Enrollment: 40 estimated patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• women that have regular menses (menstrual cycle length 21-35 days)
• women who will come visits regularly
• women that are trying to conceive more than 1 year if women age is less than 35 years or more than 6 months if women age is >35 years

Exclusion criteria

• women who do not menstruate regularly
• women that use hormonal contraception
• women who take drugs that will interfere with steroid hormone metabolism

Trial design

40 participants in 1 patient group

subfertile women

Description:

Subfertile women with regular menses (menstrual cycle length range from 21 to 35 days) will be examined by transvaginal ultrasonography at menstruation, before the anticipated date of ovulation and after ovulation. Serum hormone levels will be measured at menstruation, before ovulation and after ovulation with a serial manner.

Treatment:

Diagnostic Test: Serum progesterone levels