Seroprevalence of Pertussis Among Children and Adolescents in Croatia

University Hospital for Infectious Diseases, Croatia

Status

Unknown

Conditions

Immunogenicity, Vaccine

Treatments

Diagnostic Test: ELISA IgG Testkit

Study type

Interventional

Funder types

Other

Industry

Identifiers

NCT04725669

UHID-06

Details and patient eligibility

About

Pertussis is a vaccine preventable disease caused by Bordetella pertussis. Older children and adolescents with pertussis continue to be a significant source of infection for incompletely vaccinated infants who are in harm for developing severe disease. The primary objective of our study is to estimate the duration of protection elicited by the current vaccination schedule against pertussis in Croatia.

Enrollment

1,500 estimated patients

Sex

All

Ages

6 to 18 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

children and adolescents from 6 to 18 years of age treated through Emergency room and/or Day hospital of Pediatric Infectious Diseases Department at UHID;
appropriate vaccination with pertussis component containing vaccine by date and at the appropriate time, according to Croatian NIP proven by insight in the Vaccination Record Card
written informed consent obtained from the subject's parent or caregiver, as well as from participants ≥ 16 years old.

Exclusion criteria

children under 6 years
children and adolescents with acute respiratory symptoms
children and adolescents with pertussis-like illness within 12 months
children and adolescents with unknown, uncompleted or irregular vaccination record
inpatients
children and adolescents with immunodeficiencies