Seroprevalence of SARS CoV 2 Antibodies in Previously Undiagnosed Healthcare Workers

Mayo Clinic

Status: Completed

Conditions: COVID-19; SARS-CoV 2

Treatments: Other: Serologic testing

Study type: Interventional

Funder types: Other

Identifiers

NCT04383587

20-004054

Details and patient eligibility

About

The purpose of this study is to identify healthcare workers with SARS CoV 2 antibodies who have not been previously diagnosed and are presumed COVID-19 negative, then determine the level of immunity in this population which could inform further decisions about widespread antibody testing in a healthcare worker population.

Full description

Enrolled participants will complete a survey gauging their level of confidence they will be antibody positive. Participants will then complete serologic testing for SARS CoV 2 IgG antibodies. The study will characterize the prevalence of antibody positivity in this population and assess whether there is a correlation between a pre-test confidence level using a Likert scale and actual antibody positivity.

Enrollment: 300 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years old.
• Mayo Clinic employee in procedural and surgical area.
• Suspected COVID-19 exposure.
• Completed PCR test twice with negative results.

Exclusion criteria

• Refusal to participate in this study.

Trial design

Primary purpose: Health Services Research

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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300 participants in 1 patient group

Serologic Arm

Other group

Description:

Enrolled participants will have COVID19 IgG antibody testing performed.

Treatment:

Other: Serologic testing