Serotonin/Dopamine Antagonism of Cocaine Effect: 2 - 2

National Institutes of Health (NIH)

Status and phase: Terminated; Phase 2

Conditions: Cocaine-Related Disorders

Treatments: Drug: Risperidone

Study type: Interventional

Funder types: Other U.S. Federal agency; NIH

Identifiers

NCT00000310

NIDA-09330-2

R01-09330-2

Details and patient eligibility

About

The purpose of this study is to evaluate use of risperidone with cocaine abusers. Study measures incorporate an appropriate integration of behavioral and neurobiological indices.

Full description

Risperidone in low doses is compared with placebo in a 6-week randomized trial. Subjects also receive supportive counseling. Outcome measure include rating of behavior, mood, drug abuse, global function, and urine toxicology.

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Cocaine abuse or dependence

Exclusion criteria

Dependence on other drugs. Major psychiatric illness