Serpin C and Soluble Fms-like Tyrosine Kinase-1 Levels in Normotensive Pregnant Women May Predict the Development of Preeclampsia

Benha University

Status: Completed

Conditions: Pre-Eclampsia

Treatments: Diagnostic Test: ELISA

Study type: Observational

Funder types: Other

Identifiers

NCT06214702

RC 7.1.2024

Details and patient eligibility

About

Evaluation of the predictability of estimated levels of Serpin C, sFlt-1 and placental growth factor (PLGF) in blood samples obtained during the 1st trimester from normotensive pregnant women for identification of women liable to develop PE during the course of pregnancy.

Enrollment: 60 patients

Sex: Female

Ages: 25 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Normotensive pregnant women had singleton fetus presenting during the 1st trimester
• free of exclusion criteria

Exclusion criteria

• Age
• Sex
• Hypertension

Trial design

60 participants in 2 patient groups

Study group

Description:

Patients with diastolic blood pressure (DBP) after the 20th GW up ≥140 or 90 mmHg without proteinuria.

Treatment:

Diagnostic Test: ELISA

Control Group

Description:

Patients were normotensive at the 20th GW.

Treatment:

Diagnostic Test: ELISA