Serratus Anterior Block and Erector Spinae Block in Postoperative Analgesia

National Cancer Institute, Egypt

Status: Completed

Conditions: Postoperative Analgesia

Treatments: Procedure: Serratus anterior block (SAB); Drug: Saline (as a placebo); Procedure: Erector spinae block; Drug: Bupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT04579302

AP2007-50105

Details and patient eligibility

About

90 patients scheduled for thoracic cancer surgeries, allocated in 3 groups for serratus anterior block and erector spinae block and control group. during anaesthesia:total intraoperative fentanyl required will be recorded. After surgery, all patients will be connected to PCA device containing morphine solution, the amount of morphine consumed during the first 24 hours will be recorded.

Full description

90 patients scheduled for thoracic cancer surgeries, allocated in 3 groups for serratus anterior block (SAB) and erector spinae block (ESB) and control group. During anaesthesia: total intraoperative fentanyl required will be recorded. After surgery, all patients will be connected to PCA device containing morphine solution, the amount of morphine consumed during the first 24 hours will be recorded. Other secondary outcomes are: numerical rating scales and postoperative pulmonary functions.

Enrollment: 90 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with class II physical status (American Society of Anaesthesiologists) ,
• Age between 18-70 years,
• Scheduled for thoracic cancer surgery

Exclusion criteria

• Patient refusal.
• Local infection at the site of the block.
• Cardiac dysfunction (ejection fraction <45%).
• Significant respiratory disorders.
• Preexisting neurological or psychiatric disease.
• Allergy to one of the study drugs.
• Pregnancy.
• Coagulopathy

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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90 participants in 3 patient groups

serratus anterior block

Experimental group

Description:

serratus anterior block with 20 ml bupivacaine

Treatment:

Drug: Bupivacaine

Procedure: Serratus anterior block (SAB)

erector spinae block

Experimental group

Description:

erector spinae block with 20 ml bupivacaine

Treatment:

Procedure: Erector spinae block

Drug: Bupivacaine

control group

Sham Comparator group

Description:

sham block with 20 ml saline

Treatment:

Drug: Saline (as a placebo)